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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
24.24
Human Site:
S685
Identified Species:
33.33
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S685
H
S
P
D
A
V
Q
S
Q
R
L
A
H
A
L
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S685
H
S
P
D
A
V
Q
S
Q
R
L
A
H
A
L
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
S683
H
S
P
D
A
A
Q
S
Q
R
L
A
H
A
L
Dog
Lupus familis
XP_532459
1267
140567
S669
H
G
P
E
A
V
Q
S
Q
R
L
A
H
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
S686
H
S
P
E
A
V
Q
S
Q
R
L
A
H
A
L
Rat
Rattus norvegicus
P46462
806
89330
A264
A
V
A
N
E
T
G
A
F
F
F
L
I
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
T624
S
F
V
A
M
I
A
T
S
Q
N
Q
H
S
L
Chicken
Gallus gallus
XP_418655
1290
143066
S693
N
S
P
E
T
V
Q
S
S
R
L
A
Y
V
L
Frog
Xenopus laevis
P23787
805
89193
G263
R
A
V
A
N
E
T
G
A
F
F
F
L
I
N
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
A264
A
V
A
N
E
T
G
A
F
F
F
L
I
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
T259
A
R
A
V
A
N
E
T
G
A
F
F
F
L
I
Honey Bee
Apis mellifera
XP_397107
1069
120490
P527
I
E
D
I
M
R
S
P
P
Y
F
V
H
T
H
Nematode Worm
Caenorhab. elegans
P54812
810
89622
G268
R
A
V
A
N
E
T
G
A
F
F
F
L
I
N
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
N840
M
G
P
E
A
T
Y
N
S
R
L
A
Q
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
I273
T
G
A
F
F
F
C
I
N
G
P
E
I
M
S
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
D501
L
H
E
T
S
N
L
D
K
T
Q
K
L
I
M
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
Q714
Q
N
P
G
L
P
A
Q
L
Q
T
L
E
P
E
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
0
N.A.
13.3
60
0
0
N.A.
6.6
6.6
0
40
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
13.3
N.A.
40
80
6.6
13.3
N.A.
26.6
6.6
6.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
0
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
12
24
18
42
6
12
12
12
6
0
42
0
30
0
% A
% Cys:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
18
0
0
0
6
0
0
0
0
0
0
0
% D
% Glu:
0
6
6
24
12
12
6
0
0
0
0
6
6
0
6
% E
% Phe:
0
6
0
6
6
6
0
0
12
24
36
18
6
0
0
% F
% Gly:
0
18
0
6
0
0
12
12
6
6
0
0
0
0
12
% G
% His:
30
6
0
0
0
0
0
0
0
0
0
0
42
0
6
% H
% Ile:
6
0
0
6
0
6
0
6
0
0
0
0
18
18
6
% I
% Lys:
0
0
0
0
0
0
0
0
6
0
0
6
0
0
0
% K
% Leu:
6
0
0
0
6
0
6
0
6
0
42
18
18
6
48
% L
% Met:
6
0
0
0
12
0
0
0
0
0
0
0
0
6
6
% M
% Asn:
6
6
0
12
12
12
0
6
6
0
6
0
0
12
12
% N
% Pro:
0
0
48
0
0
6
0
6
6
0
6
0
0
6
0
% P
% Gln:
6
0
0
0
0
0
36
6
30
12
6
6
6
0
0
% Q
% Arg:
12
6
0
0
0
6
0
0
0
42
0
0
0
0
0
% R
% Ser:
6
30
0
0
6
0
6
36
18
0
0
0
0
6
6
% S
% Thr:
6
0
0
6
6
18
12
12
0
6
6
0
0
6
0
% T
% Val:
0
12
18
6
0
30
0
0
0
0
0
6
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
6
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _